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HELP needed - MS? Seizures? Epileptic?

Dear Dr. Joshua:
I desperately need your assistance -Here are my labs/MRI's - I go to Dr's and no one has SPECIFICALLY said what is going on - Please....if you would - shed some light on the possibilities/probability. Thank you so very much in advance.

Hi, I'm a 44 yr. old female. I went to the Dr. in 2002 due to multiple
cold sore outbreaks on lips, on top of nose and in nose. Right leg had
severe pain like lightening striking. Chalked up to lawn mowing accident
in 95. I have 3.5 years worth of blood work.

12/11/02: Hemogram: WBC 9.2, RBC 4.66, Hemoglobin 14.6, Hematocrit
41.9, MCV 89.8, MCH 31.3, MCHC 34.8, RDW 12.8, PLATELET COUNT 261, MPV
8.8, WBC DIFF: SEG NEUTROP 59.1, LYMPHOCYTE 31.3, MONOCYTE 7.9, BASO - .4,
ABS NEUT - 5.5, ABS LYMP 2.9, ABS MONO .7, ABS EOSINOPHIL .1, ABS BASO
.0, ANA - NEG, RHEUM FACT - 55.9, TSH 1.76

1/03/2003:
Herpes Simplex IgG 5.12, Hepatitis B / C Neg
CD2 TCELL% 95 CD2 TCELL # 2716 CD2+DR+TCELL% 5
CD3 93 CD3 2640
CD4 60 CD4 1707
CRYOGLOBULIN: 56
ALK PHOS: 198
C02: 34
WBC 8.26, RBC 4.95, Hemoglobin 15.0, Hematocrit 44.2, MCV 89.3, MCH
30.3, MCHC 33.9, RDW 13.1, PLATELET COUNT 253, MPV 10.3,
NEUT 51.8, LYMPH 29.8, MONOCYTE 6.5, BASO - .6, ABS NEUT - 5.10, ABS
LYMP 2.46, ABS MONO .54, ABS EOSIN .11, ABS BASO .05, CRP <0.3, RHEU FAC
- 55

10/09/03: Hepatic Profile: Total Protein 6.9, Albumin 3.5, Globulin
3.4, A/G Ratio 1.0, AST 18, ALT 20, Alk Phos 169, Bilirubin Total .5,
LDH 134, ELECTROLYTES: Sodium 142, Potass 4.4, Chloride 107, C02 27,
Anion Gap 12, Magnes 2.1, Phosph 3.2, Uric Acid 4.8
WBC 9.1, RBC 4.60, Hemoglobin 14.1, Hematocrit 40.7, MCV 88.5, MCH 30.7,
MCHC 34.7, RDW 12.5, PLATELET COUNT 253, MPV 8.3,
SEG NEUTROP 60.6, LYMPHOCYTE 28.7, MONOCYTE 8.4, BASO - .3, ABS NEUT -
5.5, ABS LYMP 2.6, ABS MONO .8, ABS EOSINOPHIL .2, ABS BASO .0,

1/16/04: A/G Ratio 1.0, Albumin 3.8, ALT 36, Alk Phos 177,
B/C Ratio: 17, BUN: 17, Calcium 9.4, Chloride 102, C02 31,Creatine 1.0,
GGT 20, Globulin 3.7, Glucose RAND 137, Potass: 3.7 LDH 140, Magnes 2.0,
Sodium 141, Bilirubin .4 Phos: 3.8, Total Protein 7.5, Uric 5.3
WBC 9.3, RBC 4.67, Hemo 14.8, Hema 42.4, MCV 90.9, MCH 31.6, MCHC 34.8,
RDW 12.7, PLATELET 289, MPV 9.2, SEG NEUT 58.0, LYMP 31.6, MONO 8.0,
EOSINO 1.9, BASO .5, ABS NEUT 5.4, ABS LYMP 2.9, ABS MONO .7, ABS EOSIN
.2, ESR 15

2/10/04: BUN 18, Calcium 9.6, Glucose 113, Sodium 142, Potass 3.5,
Chloride 103, C02 32, Anion Gap 11, Magnes 2.2
Phosp 3.8, T4 Total 7.8, TSH 2.83

FINAL: 12/23/05
BUN 15, Calcium 9.3, Creatine 1.2, Glucose 103, Sodium 136, Potass 3.6,
Chloride 103, C02 29, Anion 8, T4 6.3, T4 Free .78, TSH 2.14, WBC 5.8,
RBC 4.5 HEMO 13.6, HEMA 38.7, MCV 86.8, MCH 30.4, MCHC 35, RDW 12.2,
PLATELET 269, MPV 8.0, SEG NEUT 55.4, LYMPH 36.5, MONO 7.3, EOSIN .2,
BASO .6, ABS NEUT 3.2, ABS LYMPH 2.1, ABS MONO .4, ABS EOSIN .0

MRI's
6/03: A single focal area of increased signal is noted w/in the right cerebral hemisphere in the centrum semiovale, a nonspecific finding. IMPRESSION: No definitive evidence of a demyelinating process.

Cerivical Spine: There are no findings suggestive of a demyelinating process
US Abdominal Worksheet: Slightly hyperechoic liver in Left Lobe

Alkaline Phos. - + bonescan - neg MRI - neg

8/04: On T2 weighted and FLAIR images, are multiple small focal areas of increased signal intensity involving the deep cerebral white matter bilaterally from teh frontal to the occipital lobes. Many of the foci are quite small and are more numerous on the right than on the left, and most of the foci are in subcortical distributions.

12/05: On T2 weighted and FLAIR images, there are multiple small focal areas of increased signal intensity involving cerebral white matter bilaterally from the frontal to the occipital lobes. Most of the white matter foci are in subcortical distributions.

6/06: On T2 weighted and FLAIR images, there are multiple small focal areas of increased signal intensity involving cerebral white matter bilaterally from the frontal to the occipital lobes. Most of the white matter foci are in subcortical distributions

EEG (48 hrs) 7/18/06-7/20/06: Posterior dominant rhythm in the 9-11 Hz alpha range and 20-40 microvolt amplitude range seen in the occipital leads symmetrically during restful wakefulness. Beta activity in 15-20 Hz and less than 20 microvolt amplitude seen in frontal central regions intermittently and symmetrically. Occasional bi-temperal slowing in the 3-5 Hz range and 20-40 micro. associated with abnormal events - no definite epileptiform activity recorded. No seizures recorded.

Impression: Mildly abnormal 48-hr ambulatory EEG due to intermittent bi-temporal slowing. This may be due to an underlying structural abnormality, which may predispose patient to epileptiform activity. Patient had several non-epileptiform events recorded.

8/1/06 Neuro visit Impression: Findings, signs and symptoms most consistent with underlying difficulty with episodes of transient myoclonic jerks. These are not associated with underlying seizure activity as seen by her 48-hr. EEG.

Ok...PLEASE...........................Help - everything seems to not jive and I'm totally confused.
Thank you!

Answers:


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